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Effect of dexmedetomidine as an adjunct for ultrasound-guided low serratus anterior block combined with rectus sheath block on postoperative pain and gastrointestinal function recovery in laparoscopic gastrointestinal surgery

Effect of dexmedetomidine as an adjunct for ultrasound-guided low serratus anterior block combined with rectus sheath block on postoperative pain and gastrointestinal function recovery in laparoscopic gastrointestinal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084914
Enrollment
Unknown
Registered
2024-05-28
Start date
2024-05-30
Completion date
Unknown
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal Surgery

Interventions

Group N:Ultrasound-guided low serratus anterior block combined with rectus sheath block
Group D:Dexmedetomidine as an adjunct for ultrasound-guided low serratus anterior block combined with rectus sheath block

Sponsors

Southern Medical University Southern Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
24 Years to 78 Years

Inclusion criteria

Inclusion criteria: 1. Voluntary signing of informed consent form; 2. Aged 18 years or older; 3. BMI between 18.5 and 28 kg/m^2; 4. ASA grade I-III; 5. Undergoing elective laparoscopic gastrointestinal surgery; 6. Participants or their representative consents to provide relevant data.

Exclusion criteria

Exclusion criteria: 1. Pregnancy and breastfeeding; 2. Long-term opioid use; 3. Aallergy or intolerance to study-related medications; 4. Severe coagulation disorders; 5. Participants who are unable to read, comprehend, or communicate; 6. Participants whom the investigator deems unsuitable for participation in this trial.

Design outcomes

Primary

MeasureTime frame
Hydromorphone consumption within 24 hours postoperatively;

Secondary

MeasureTime frame
Pain-related indicators: Hydromorphone consumption at 2, 48, and 72 hours postoperatively; Pain numeric rating scores at rest and during coughing at 2, 24, 48, and 72 hours postoperatively; Amount of rescue analgesia used in the ward and the number of PCA (Patient-Controlled Analgesia) presses; Patient satisfaction with pain relief at 24 hours postoperatively;Gastrointestinal function-related indicators: Time to start and tolerate oral intake of food and water postoperatively; Time to first flatus and bowel movement; Incidence of postoperative bloating, nausea, and vomiting;Other indicators: Time to active ambulation; Length of hospital stay; Incidence of postoperative adverse events and complications;

Countries

China

Contacts

Public ContactXiyang Zhang

Southern Medical University Southern Hospital

zhangxiy07@163.com+86 20 6164 1882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026