Parkinson's depression
Conditions
Interventions
Treatment group:Provide Qihuang acupuncture therapy on top of basic treatment.
Control group:Apply false needle acupuncture on top of basic treatment.
Sponsors
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: (a) Meet the diagnostic criteria for Parkinson's depression; (b) Aged 30-75 years; (c) The course of the disease is less than 10 years; (d) Hoehn-Yahr rating within 1-3; (e) Depression was classified as mild depression (f) Those receiving anti-PDD medication and taking steady doses, or those not receiving medication; (g) Clear consciousness, stable vital signs, no obvious intellectual disability, no obvious hearing impairment, no history of suicide, self-harm or inclination; (h) The person who signed the informed consent.
Exclusion criteria
Exclusion criteria: (a) Parkinson's syndrome and Parkinson's syndrome caused by various causes such as cerebrovascular disease and poisoning; (b) Those with more serious diseases, such as serious liver, kidney, blood, neoplasms, endocrine diseases or pain; (c) Participants in clinical trials of other drugs and acupuncture simultaneously; (d) Depression is classified as major depression, mental illness, or a history or tendency to commit suicide or self-harm; (e) Persons who are deaf or have communication difficulties; (f) Persons with a history of alcohol or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale-24, HAMD-24; | — |
Secondary
| Measure | Time frame |
|---|---|
| functional connectivity,FC;Nrf2 ;NLRP3;Caspase-1;Hoehn-Yahr;UPDRS?; | — |
Countries
China
Contacts
Public ContactChen Zhenhu
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Outcome results
None listed