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Cancelled by the investigator. A multicenter, randomized, parallel controlled clinical trial of acupotomy release combined with PRP injection for the treatment of knee osteoarthritis

A multicenter, randomized, parallel controlled clinical trial of acupotomy release combined with PRP injection for the treatment of knee osteoarthritis

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084882
Enrollment
Unknown
Registered
2024-05-27
Start date
2024-06-01
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Acupotomy combined with PRP injection group:Ordinary acupuncture and acupotomy combined with PRP injection therapy was performed
Acupotomy group:Ordinary acupuncture combined with acupotomy therapy
PRP injection group:Ordinary acupuncture combined with PRP injection was performed
Ozone water group:Ordinary acupuncture combined with ozone water injection was performed
Acupotomy combined with septum aconite cake moxibustion group:Ordinary acupuncture and acupotomy combined with septal aconite cake moxibustion

Sponsors

The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Diagnostic criteria of Western medicine: formulated with reference to the Guidelines for the Diagnosis and Treatment of Osteoarthritis issued in 2018: ?The patient's knee pain has recurred in the past 1 month; ?X-ray of the knee joint showed that the patient had reduced joint space, subchondral osteosclerosis and cystic changes, or osteophytes around the joints; ?The patient's synovial fluid (at least twice) is viscous and clear, and the WBC < 2000 pcs/mL; ?Patient age=50; ?The morning stiffness = 30 min; ?The patient has a bone fricative during activity. In addition to?, any of ?, ?, ?, ?, and? can be added to make a diagnosis of knee osteoarthritis. (2) Diagnostic criteria of traditional Chinese medicine: The diagnostic criteria for diseases and syndromes of traditional Chinese medicine refer to the diagnostic criteria for knee paralysis (liver and kidney deficiency type) in the "Guidelines for the Diagnosis and Treatment of Knee Osteoarthritis" formulated in 2020:? Main symptoms: soreness and weakness of the knee joint, dull pain.?Secondary symptoms: soreness and weakness in the waist, aggravation of waist and knee soreness during exertion, accompanied by symptoms such as dizziness and tinnitus. The tongue is red, little lichen, and the pulse is thin and weak. (3) Aged between 40-80 years old; (4) Discontinuation of other therapies and drugs that may affect the observed indicators of this study during the period of acceptance of this study method; (5) There are no obvious contraindications to acupuncture treatment; (6) All patients had a single-knee disease; (7) All patients and their families have informed consent and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with severe heart, liver and kidney impairment, blood and respiratory diseases, endocrine diseases, hematological tumor diseases, rheumatic immune diseases and severe mental diseases; (2) Patients with knee fractures or tuberculosis and other diseases; (3) Pregnant and lactating females; (4) Patients with allergy to local anesthetics, poor skin condition on the knees, and those who are susceptible to infection are treated; (5) Patients with bleeding tendency and coagulation dysfunction; (6) Patients with certain cognitive impairment or speech and communication impairment;

Design outcomes

Primary

MeasureTime frame
Western Ontario and Mcmaster Universities Osteoarthritis Index;

Secondary

MeasureTime frame
VAS ;Traditional Chinese Medicine Syndrome Points;Medical Outcomes Study Short-Form 36;

Countries

China

Contacts

Public ContactLI Fei

The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine

316029622@qq.com+86 199 6551 0509

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026