cognitive impairment
Conditions
Interventions
Youth Moxibustion Group:acupoint stimulation
Elderly moxibustion group:acupoint stimulation
Sponsors
Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) For thoracolumbar spine surgery, the surgical incision is 10-15cm, and the operation lasts 2-4 hours 2) Gender is not limited; age 18-90 years old 3) BMI: 18.5-28kg/m2; male waist circumference is less than 85CM, female waist circumference is less than 80CM 4) Preoperative ASA score I-III; the patient has no severe hearing and visual impairment and is able to read. 5) Informed consent of the patient.
Exclusion criteria
Exclusion criteria: 1) There are diseases such as fever before surgery that can affect the body's inflammatory stress response indicators 2) Severe cardiopulmonary disease, severe liver and kidney insufficiency; history of dementia and mental illness 3) Have a history of brain and abdominal surgery 4) Current use of sedatives, antidepressants, or corticosteroids; those on antibiotic therapy 5) Daily use of probiotics, nursing home diet 6) Alcohol and drug dependence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE;MoCA;Intestinal microbiota;3D-CAM; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory biomarkers;Oxidative stress biomarkers;Brain injury markers; | — |
Countries
China
Contacts
Public ContactZhongmeng Lai
Fujian Medical University Union Hospital
Outcome results
None listed