Lumbar spine disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age 18 to 70 years old, body mass index 18 to 30 kg/m²; (2)ASA??? ; (3)Patients can have good communication skills and can assess pain numerical scores ;(4) Operation time <4 hours; (5)Posterior lumbar intervertebral fusion surgery (1-3 diseased segments); ?(6)Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Body mass index =30 kg/m², weight less than 30kg or more than 100kg, and alcoholism; 2) puncture point infection, spinal cord injury, or a combination of multiple injuries or malignant tumors; 3) symptoms of intracranial hypertension, a history of cerebrovascular accidents, or severe hypertension; 4) patients with long-term use of corticosteroids or analgesics who are allergic to ropivacaine local anesthetics; 5) patients with hypovolemia, blood diseases, or abnormal coagulation function undergoing anticoagulation therapy; 6) those with clinically significant cardiovascular, lung, liver, or kidney diseases; 7) individuals with speech dysfunction, mental illness, severe anxiety, or depression; 8) patients receiving chronic pain treatment; 9) individuals with a history of previous lumbar surgery or QLB combined with other nerve blocks; 10) those with cerebrospinal fluid leakage or suspected meningeal rupture.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative consumption of remifentanil; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale,VAS;Recovery quality;BCS(Bruggrmann comfort scale);Hemodynamics;C-reactive protein;Adverse reactions included restlessness, postoperative nausea and vomiting, quadriceps muscle strength, etc;Intraoperative consumption of propofol;Intraoperative dosage of sevoflurane;Postoperative recovery index;Length of postoperative hospital stay;Hospital costs;Remedial analgesia;Pittsburgh Sleep Quality Index (PSQI);Mini-Mental State Examination(MMSE);Anxiety score;Likert scale;Richmond Agitation and Sedation Scale(RASS); | — |
Countries
China
Contacts
Guangxi Zhuang Autonomous Region People's Hospital