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Research on the application of general anesthesia combined with two different nerve block methods in lumbar spine surgery

Research on the application of general anesthesia combined with two different nerve block methods in lumbar spine surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084870
Enrollment
Unknown
Registered
2024-05-27
Start date
2024-05-27
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar spine disease

Interventions

Experimental Group 1:After general anesthesia induction, a total of 40 ml of 0.4% ropivacaine was used, and 20 ml of each side was given for erector spinae plane block.
Experimental Group 2:After general anesthesia induction, a total of 40 ml of 0.4% ropivacaine was used, and 20 ml of each side was given for quadratus lumborum block.

Sponsors

Guangxi Zhuang Autonomous Region People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age 18 to 70 years old, body mass index 18 to 30 kg/m²; (2)ASA??? ; (3)Patients can have good communication skills and can assess pain numerical scores ;(4) Operation time <4 hours; (5)Posterior lumbar intervertebral fusion surgery (1-3 diseased segments); ?(6)Agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Body mass index =30 kg/m², weight less than 30kg or more than 100kg, and alcoholism; 2) puncture point infection, spinal cord injury, or a combination of multiple injuries or malignant tumors; 3) symptoms of intracranial hypertension, a history of cerebrovascular accidents, or severe hypertension; 4) patients with long-term use of corticosteroids or analgesics who are allergic to ropivacaine local anesthetics; 5) patients with hypovolemia, blood diseases, or abnormal coagulation function undergoing anticoagulation therapy; 6) those with clinically significant cardiovascular, lung, liver, or kidney diseases; 7) individuals with speech dysfunction, mental illness, severe anxiety, or depression; 8) patients receiving chronic pain treatment; 9) individuals with a history of previous lumbar surgery or QLB combined with other nerve blocks; 10) those with cerebrospinal fluid leakage or suspected meningeal rupture.

Design outcomes

Primary

MeasureTime frame
Intraoperative consumption of remifentanil;

Secondary

MeasureTime frame
visual analogue scale,VAS;Recovery quality;BCS(Bruggrmann comfort scale);Hemodynamics;C-reactive protein;Adverse reactions included restlessness, postoperative nausea and vomiting, quadriceps muscle strength, etc;Intraoperative consumption of propofol;Intraoperative dosage of sevoflurane;Postoperative recovery index;Length of postoperative hospital stay;Hospital costs;Remedial analgesia;Pittsburgh Sleep Quality Index (PSQI);Mini-Mental State Examination(MMSE);Anxiety score;Likert scale;Richmond Agitation and Sedation Scale(RASS);

Countries

China

Contacts

Public ContactGong Zheng

Guangxi Zhuang Autonomous Region People's Hospital

815117450@qq.com+86 133 6761 7092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026