Sepsis
Conditions
Interventions
Sepsis group:None
Sponsors
Xijing Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: sepsis group: (1) age =65 years; (2) Sepsis was diagnosed according to Sepsis3.0 criteria; (3) Agree to participate in this project and have signed the informed consent form. Non-sepsis group: (1) age =65 years; (2) Gender and comorbidities were matched with the patient group, and patients were in the stable stage of chronic diseases; (3) Agree to participate in this project and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: sepsis group: (1) recent (<1 month) history of immunosuppressive drugs and chemotherapy drugs; (2) combined with malignant tumors and immune system diseases; (3) those who are mentally ill or mentally retarded or otherwise unable to cooperate; (4) patients with acute or chronic intestinal diseases (Crohn's disease, ulcerative colitis, irritable bowel syndrome, etc.); (5) history of alcohol/drug abuse; (6) having received or being treated with fecal microbiota transplantation; (7) other conditions considered by the investigator to be unsuitable for enrollment. Non-sepsis group: (1) recent (<1 month) history of immunosuppressive drugs and chemotherapy drugs; (2) combined with malignant tumors and immune system diseases; (3) those who are mentally ill or mentally retarded or otherwise unable to cooperate; (4) patients with acute or chronic intestinal diseases (Crohn's disease, ulcerative colitis, irritable bowel syndrome, etc.); (5) history of alcohol/drug abuse; (6) having received or being treated with fecal microbiota transplantation; (7) other conditions considered by the investigator to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endotoxin(LPS);Intestinal fatty acid-binding protein(I-FABP);Diamine oxidase(DAO);D-lactic acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events; | — |
Countries
China
Contacts
Public ContactXiaoxuan Ning
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed