Atrial Fibrillation
Conditions
Interventions
pulmonary vein isolation only group:pulmonary vein isolation
pulmonary vein isolation plus Low-Voltage Areas Ablation During Sinus Rhythm group:pulmonary vein isolation plus Low-Voltage Areas Ablation During Sinus Rhythm
pulmonary vein isolation plus Low-Voltage Areas Ablation During Atrial Fibrillation group:pulmonary vein isolation plus Low-Voltage Areas Ablation During Atrial Fibrillation
Sponsors
The affiliated Yantai Yuhuangding Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Men aged = 18 years and = 80 years old, or non pregnant and lactating women; 2. Patients with symptomatic persistent atrial fibrillation: The medical record shows a duration of atrial fibrillation of = 7 days or a history of persistent atrial fibrillation, and any of the following conditions are met: i) Dynamic electrocardiogram recording within 90 days indicates complete atrial fibrillation; Ii) Two electrocardiograms (from any form of electrocardiogram record) with an interval of at least 7 days within a year showing atrial fibrillation; c) Those who have received at least one type of Class I or III AAD treatment but have poor efficacy or cannot tolerate it, or do not receive Class I or III AAD treatment. 3. Fully understand this study and voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1: Patients who had previously undergone atrial fibrillation, atrial tachycardia, or atypical atrial flutter ablation 2: Preoperative combined atrial tachycardia (=30S) and atypical atrial flutter 3: Left atrial diameter >55mm 4: Left ventricular ejection fraction <35% 5: Left atrial thrombus 6: Postoperative cardiac surgery 7: After valve replacement 8: After permanent pacemaker implantation 9: hypertrophic cardiomyopathy 10: Patients with moderate-to-severe aortic valve disease, moderate-to-severe mitral stenosis, and severe other valvular disease 11: Hemorrhagic stroke within 6 months 12: Transient ischemic attack or ischemic stroke within 1 month 13: Mental disorder or history of mental illness and inability to cooperate voluntarily 14: Breastfeeding, pregnancy and women planning or likely to become pregnant 15: Life expectancy <12 months 16: Participating in other interventional clinical trials 17: The researchers judged that it was not suitable for inclusion in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of no atrial arrhythmias greater than 30 seconds; | — |
Secondary
| Measure | Time frame |
|---|---|
| No use of antiarrhythmic drugs and no occurrence of atrial fibrillation exceeding 30 seconds;No use of antiarrhythmic drugs and no occurrence of atrial tachycardia/flutter exceeding 30 seconds;Atrial fibrillation load;Ablation time and surgical time;complications; | — |
Countries
China
Contacts
Public ContactChu Hongxia
The affiliated Yantai Yuhuangding Hospital of Qingdao University
Outcome results
None listed