orthopedics surgery
Conditions
Interventions
Control group:The same dose of saline was infused continuously
Dexmedetomidine Intervention Group 1:Dexmedetomidine (0.05 ug/kg/h) was infused continuously until 8:00 on 1-day postoperatively.
Dexmedetomidine Intervention Group 2:Dexmedetomidine (0.05 ug/kg/h) was infused continuously until 8:00 on 3-day postoperatively.
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 age =65,2 ASA grade II-III, 3 elective orthopaedic surgery, 4 PQSI score =5, MOCA score =26.
Exclusion criteria
Exclusion criteria: 1 severe sinus bradycardia (HR <50 beats/minute) or II-III degree atrioventricular block; 2 dementia or previous history of stroke; 3 preoperative depression or anxiety; 4 inability to communicate because of language or hearing problems; 5 patients withdrew from the study, 6 patients were transferred to ICU after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of delirium;Sleep score;Pain score;Postoperative complications or adverse events;Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactXinqi Cheng
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed