Non-ST Elevation Myocardial Infarction (NSTEMI)
Conditions
Interventions
Gold Standard:The gold standard for the diagnosis of NSTEMI follows the fourth edition of the universal definition of myocardial infarction: the detection of at least one troponin level above the 99th
(2) There is a new onset of ischemic ECG changes
(3) There is pathological Q wave on the ECG
(4) Imaging evidence, such as echocardiography or cardiac MRI, shows loss of viable myocardium or segmental wall motion abnormalities consistent with the cause of ischemia
(5) Coronary angiography or autopsy reveals thrombus formation in the coronary artery.
Index test:Copeptin
High-sensitivity Cardiac Troponin
Sponsors
Zhongshan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.The patient must be at least 18 years old. 2.The patient presented with symptoms consistent with suspected NSTEMI, including chest pain/discomfort, angina pectoris, radiating pain to the upper extremities, referred pain to the maxilla, thoracic/cervical/abdominal discomfort, dyspnea, diaphoresis, emesis/nausea, and vertigo/lightheadedness. 3.The time elapsed from symptom onset to seeking medical attention is within a 6-hour window 4.The patient agrees to comply with the relevant requirements of this research protocol.
Exclusion criteria
Exclusion criteria: 1.Patients with chest pain due to trauma 2.The patient's electrocardiogram (ECG) reveals sustained elevation of the ST segment, indicative of a ST-elevation myocardial infarction (STEMI) 3.Severe renal insufficiency requiring dialysis in end-stage renal failure patients. 4.Patients who have suffered muscle injuries or undergone major surgery within the past four weeks. 5.Pregnant and lactating individuals 6.The informed consent form is not comprehensible or agreeable to patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Copeptin;High-sensitivity Cardiac Troponin;sensitivity;specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Negative predictive value;Major Adverse Cardiovascular Events; | — |
Countries
China
Contacts
Public ContactSong.zhenju
Zhongshan Hospital Affiliated to Fudan University
Outcome results
None listed