immune thrombocytopenia
Conditions
Interventions
Treatment effective/ineffective group:None
Sponsors
Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School
Eligibility
Sex/Gender
All
Age
15 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? The patient meets the diagnostic criteria for immune thrombocytopenia; ? Willing to cooperate with this study, with good compliance; ? Regularly taking the same dose of tacrolimus for at least 5 days; ? Monitoring the blood concentration of tacrolimus and other related laboratory tests; ? Complete clinical data and relevant laboratory test results.
Exclusion criteria
Exclusion criteria: ? The patient's platelet count is less than 10x10 ^ 9/L or there is severe bleeding; ? Use of platelet promoting drugs, immunoglobulins, high-dose methylprednisolone, rituximab, etc ? Poor patient compliance and inability to cooperate with the study; ? Patients with severe comorbidities, such as tumors, severe infections, severe trauma, cirrhosis, etc; ? Pregnant and lactating patients; ? The clinical data and relevant laboratory test results are incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood concentration of tacrolimus;Concentration of tacrolimus in PBMC; | — |
Secondary
| Measure | Time frame |
|---|---|
| genotype;CBC;erythrocyte sedimentation rate, ESR;Biochemical Examination;C-reactive protein, CRP; | — |
Countries
China
Contacts
Public ContactQing Shu
Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School
Outcome results
None listed