mdr-tb
Conditions
Interventions
Gold Standard:Sputum culture of Mycobacterium tuberculosis
Index test:TB RNA detection was performed using nucleic acid extraction reagents (Hu Pu Xi Bei No. 20200136) and Mycobacterium tuberculosis nucleic acid detection kits (RNA constant temperature amplif
Sponsors
Guangxi Zhuang Autonomous Region Chest Hospital (The Fourth People's Hospital of Guangxi Zhuang Autonomous RegionGuangxi Tuberculosis Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with multidrug-resistant tuberculosis aged = 18 years were selected to be included in the group. According to the requirements of the Work Plan for the Prevention and Control of Multidrug resistant Pulmonary Tuberculosis (2012), the multidrug-resistant pulmonary tuberculosis experts combined with the patient's medical history, chest imaging, laboratory and other related examinations, confirmed that the drug resistance test results were reported to at least the patients who were resistant to isoniazid and rifampicin at the same time. 2. The patient stated that they can adhere to completing 2 years of standardized medication and treatment.
Exclusion criteria
Exclusion criteria: 1. Other major diseases (such as severe heart failure and kidney failure) that may affect disease treatment; Individuals with symptoms such as drug related allergies to the drugs involved in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mycobacterium Tuberculosis;Positive consistency between RNA detection of Mycobacterium tuberculosis and parallel detection of sputum culture of Mycobacterium tuberculosis; | — |
Countries
China
Contacts
Public ContactYang Xiaobing
Guangxi Zhuang Autonomous Region Chest Hospital (The Fourth People's Hospital of Guangxi Zhuang Autonomous RegionGuangxi Tuberculosis Hospital)
Outcome results
None listed