None listed
Conditions
Interventions
Sponsors
Army Medical Center(Daping Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: ?18-45 years old, male or female ; ? healthy, body mass index ( BMI ) of 18.5-24.9 kg / m2 ;? in the past 1 month did not take any antibiotics, intestinal probiotics ( such as probiotics ), prebiotics, saffron, Rhodiola and other drugs ; ? Signed informed consent and agreed to participate in the study.
Exclusion criteria
Exclusion criteria: ? with gastrointestinal inflammation, tumor, gastrointestinal surgery history ; ? with serious heart, liver, kidney, lung, brain and other organic lesions ; ? previous diagnosis of anxiety, depression, schizophrenia and other mental diseases, or taking mental related drugs in the past 1 month ; ? combined with other diseases that affect the intestinal microflora, such as metabolic syndrome and autoimmune diseases ; ? patients who are participating in other clinical trials ; ? The researchers believe that other reasons are not suitable for the group or the subjects withdraw from the test for their own reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbitoa species; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastrointestinal Symptom Rating Scale (GSRS);Bristol stool scale;Symptom Checklist-90 (SCL-90);Perceived Stress Scale (PSS);Psychological stress self-evaluation test (PSET);Connor-Davidson Resilience Scale (CD-RISC);General Self-Efficacy Scale (GSES);Patient Health Questionnaire (PHQ-9);Generalized Anxiety Disorder-7 (GAD-7);Pittsburgh sleep quality index (PSQI);Blood metabolomic;Serum cytokines; | — |
Countries
China
Contacts
Public ContactYanling Wei
Army Medical Center(Daping Hospital)
Outcome results
None listed