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A prospective, open label, single center study on non-invasive diagnosis of renal cell carcinoma using CD70 specific PET imaging

A prospective, open label, single center study on non-invasive diagnosis of renal cell carcinoma using CD70 specific PET imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400084782
Enrollment
Unknown
Registered
2024-05-24
Start date
2024-05-31
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal cell carcinoma

Interventions

Index test:68Ga-NOTA-RCCB6 PET/CT

Sponsors

the First Affiliated Hospital of the People's Liberation Army Air Force Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The informed consent form must be voluntarily signed by the subject, legal guardian, or caregiver. 2. Age range from 18 to 75 years old. 3. Patients suspected of renal cell carcinoma through routine imaging examination and underwent 68Ga-PSMA PET/CT scan. 4. Routine imaging or 68Ga-PSMA PET/CT reveals suspicious lymph nodes or distant metastases. 5. Willing and capable of following the research plan.

Exclusion criteria

Exclusion criteria: 1. Received anti-tumor treatment before PET/CT scan. 2. Suffering from serious other neurological diseases, or gastrointestinal, cardiovascular, liver, kidney, blood system, respiratory system, immune deficiency, and other serious diseases. 3. Candidates have contraindications for PET/CT scanning. Including but not limited to: those who cannot accept repeated intravenous injections; Individuals who may have allergies to drugs and their components (including those with a history of severe allergies or allergic reactions, especially those who are allergic to the tested drugs); Confinement phobia. 4. Diagnosed with other malignant tumors in the past year; The candidate subjects have undergone major surgery within the past 3 months; Received (unclear efficacy or safety) experimental drug or device treatment within one month, or participated in other intervention clinical trials. 5. Pregnant or lactating women. 6. Patients who have been lost to follow-up. 7. According to the evaluation of the researchers, the subjects may have other circumstances that may affect the study or are not suitable for participation in the study.

Design outcomes

Primary

MeasureTime frame
liver SUVmean;SUVmax;Image characteristics of 68Ga-NOTA-RCCB6 PET\/CT in renal cell carcinoma and its correlation with CD70 expression;

Secondary

MeasureTime frame
Blood routine;Routine urine test;Liver and kidney function;electrolytic;Accuracy ;Sensitivity ;Specificity ;

Countries

China

Contacts

Public ContactFei Kang

the First Affiliated Hospital of the People's Liberation Army Air Force Military Medical University

2326604944@qq.com+86 29 8477 1048

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026