Hip fracture
Conditions
Interventions
Group B:Iliac fascia block using liposomal bupivacaine
Group R:Iliac fascial block using ropivacaine
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Patients with hip fracture, elective total hip arthroplasty, artificial femoral head replacement or intramedullary nail placement 2) Age =65, =90 years old, gender is not limited. 3) BMI: 18-30kg/m2 4) ASA classification II-IV 5) Able to understand and perform NRS score, QoR15 score and delirium scale score, etc. 6) Voluntarily sign the informed consent form and willing to comply with the requirements of the study protocol.
Exclusion criteria
Exclusion criteria: 1) severe cardiac, pulmonary, hepatic and renal dysfunction; 2) History of psychiatric illness or chronic use of psychotropic drugs (dementia, schizophrenia), chronic analgesic drugs, and history of alcoholism; 3) Preoperative Brief Intelligent Mental State Examination Scale (MMSE) <21 points with a diagnosis of moderate-to-severe cognitive impairment; 4) Any cerebrovascular accident such as stroke, transient ischemic attack (TIA) within 3 months; 5) Patients with presence of severe infection; 6) Preoperative PaO2 < 60 mmHg or SpO2 < 92%; 7) Participation in another clinical study of the drug within the last 30 days; 8) Hypersensitivity to the test drug;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CAM Scale;MMSE Scale;MoCA Scale;(QoR-15);Pittsburgh Sleep Quality Index;NRS; | — |
Countries
China
Contacts
Public ContactXu Min
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed