diabetes
Conditions
Interventions
Semaglutide:None
Non-Semaglutide:None
Sponsors
Tibet Autonomous Region People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Exposed group 1. =18 years old and =75 years old; 2. Diagnosed with type 2 diabetes; 3. Oral hypoglycemic agents, insulin, semaglutaide or a combination of boths; 4. HbA1c=7% and =15%; 5. Permanent residence in Lhasa for 6 months or more (altitude of 3650 m); Non-exposed group 1. =18 years old and =75 years old; 2. Diagnosed with type 2 diabetes; 3. Oral hypoglycemic agents, insulin or a combination of boths; 4. HbA1c=7% and =15%; 5. Permanent residence in Lhasa for 6 months or more (altitude of 3650 m);
Exclusion criteria
Exclusion criteria: 1. Present with diabetic ketoacidosis or diabetic hyperosmosis; 2. A medical or family history of medullary thyroid carcinoma, multiple endocrine adenomatosis type 2A or 2B; 3. Had a history of gastroparesis, uncontrolled gastroesophageal reflux disease, and gastric ulcer within 6 months before enrollment, including persistent nausea and vomiting; 4. Has serious disease of the cardiovascular, liver, endocrine, or other systems that prevents the completion of the study or affects the outcome of the study; 5. Complicated with brain organic mental disorders, alcohol and drug dependence, schizophrenia, bipolar disorder, etc.; 6. Patients at risk of suicide; 7. Conditions that prevent patients from following and completing the study protocol (known drug and alcohol abuse, etc.); 8. Pregnant or lactating women; 9. The patient has a past allergy to this product; 10. Patients who experienced adverse events during the screening period were deemed unsuitable for inclusion in this study according to the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 17-item Hamilton Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montgomery-Asberg Depression Rating Scale;Hamilton Anxiety Scale; | — |
Countries
Chian
Contacts
Public ContactLe Yunyi
Tibet Autonomous Region People’s Hospital
Outcome results
None listed