none
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Chinese people aged 18 to 70 (2) Male height 161~179CM/weight 48~76KG, female height 150~166CM/weight 41~66KG (height and weight are determined as a range based on the average height/weight ±5% of the age group according to the National Physical Fitness Monitoring Bulletin by the General Administration of Sport of the People's Republic of China, and the BMI refers to the Chinese standard of 18.5~23.9); (3) Living in a fixed geographical area for more than one year; (4) Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Previously diagnosed with impaired blood glucose, diabetes mellitus, hypertension, coronary heart disease, hyperthyroidism, hypothyroidism; (2) Previously suffered from any serious organic disease, as well as severe pulmonary, hepatic, and renal dysfunction (ALT greater than 1.5 times the upper limit of normal, creatinine greater than 61 µmol/l), psychosis, with severe infections, severe anemia, neutropenia; other serious organic heart disease; (3) Use of any prescribed medication within 30 days that may affect the results of the test; (4) Surgical or medical factors that may affect drug absorption, metabolism, distribution, or excretion; (5) Participation in a clinical drug trial within 90 days or receipt of a trial drug with less than 5 half-lives to date; (6) Whole blood or plasma donation or severe blood loss within 2 months; (7) History of multiple drug allergies; (8) A history of severe allergic disease such as asthma, anaphylaxis, and other medications; (9) Drug or alcohol abuse (weekly intake of more than 280g of ethanol equal to 8750ml of beer, 4900ml of red wine, 875ml of spirits); (10) History of smoking or consumption of any tobacco-related products within 3 months; (11) Have a bowel movement cycle of more than 3 days; (12) A history of long-term vegetarian, gluten-free, ketogenic, or other specialized diets; (13) Female subjects should be non-menstrual, non-pregnant, and non-lactating; (14) Sample size is insufficient for laboratory extraction; (15) Subject information is incomplete or not traceable in medical records; (16) Subjects deemed unsuitable by the investigator, if participation in the trial may place the subject at significant risk.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| height&weight;body composition;physical dimension;energy consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function;renal function;electrocardiogram, ECG; | — |
Countries
China
Contacts
Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine