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Exploration of the Application Value of Pre oxygenation Technology Combined with Optimal Gastroscopy Entry Timing in Painless Digestive Endoscopy Surgery

Exploration of the Application Value of Pre oxygenation Technology Combined with Optimal Gastroscopy Entry Timing in Painless Digestive Endoscopy Surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084729
Enrollment
Unknown
Registered
2024-05-23
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal diseases

Interventions

A group:After pre oxygenation and anesthesia induction, enter the gastroscopy at the time when the heart rate begins to decrease, and tilt the head back about 45 °
B group:The timing selection for gastroscopy includes disappearance of consciousness, no response to mandibular support, disappearance of eyelash reflex, and the rest is consistent with Group A
C group:No pre oxygen therapy, the rest is the same as Group A
D group:No pre oxygen therapy, the rest is the same as Group B
E group:Perform pre oxygen therapy, with the head not tilted back when entering the gastroscopy, and the rest consistent with Group D
F group:No pre oxygen therapy, the rest is the same as Group E

Sponsors

The 3rd Medical Center of the General Hospital of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: The patient is not less than 18 years old, regardless of gender or ethnicity; Intended for non emergency gastroscopy and colonoscopy diagnosis and treatment under deep sedation; ASA grades I to III.

Exclusion criteria

Exclusion criteria: (1) Refusal to participate in this study; (2) Elderly patients over 73 years old; (3) Individuals with mental or neurological disorders, suspected dementia, or memory impairment; Severe impairment of auditory, visual, and language system functions; COPD patients (4) with nasal obstruction and inability to receive nasal ventilation; (5) Identify or suspect the misuse or long-term use of anesthetic sedatives and analgesics; (6) Individuals with contraindications or allergies to midazolam, dacron, propofol, and etomidate; (7) Acute phase of upper respiratory tract infection with symptoms such as cough and sputum production; (8) Full stomach, fasting for less than 8 hours, abstaining from drinking for less than 2 hours, and taking the last laxative less than 3 hours before diagnosis and treatment; (9) Patients with achalasia of the cardia who have not undergone surgical treatment and suspected upper gastrointestinal obstruction with a risk of reflux aspiration; (10) Cervical spondylosis with severe restriction of head tilt back.

Design outcomes

Primary

MeasureTime frame
The state of gastroscopy entering the glottis of the pharynx (including movement and morphology);

Secondary

MeasureTime frame
First rate of decrease in oxygen saturation;The time when the doctor found the pear shaped pit;The time when the physician found the entrance to the esophagus;Number of chin supports;Proportion of fully exposed glottal structure;Intraoperative body movement incidence;The incidence of coughing during surgery;Incidence of hypoxemia (SpO2<92%);

Countries

CHINA

Contacts

Public ContactBOYAN LIU

The 3rd Medical Center of the General Hospital of the People's Liberation Army of China

2567257595@qq.com+86 159 0176 9207

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026