skin allergy
Conditions
Sponsors
Wuxi No.2 People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients: (1) =18 years old; And the skin appeared allergic symptoms, skin itching, tingling, rash and other phenomena. The diagnostic criteria of skin allergy were: ? Itching and dry skin; ? typical morphology and distribution of skin lesions; ? When the weather changes, pressure and other external conditions occur, the skin will appear peeling or itching; ? Serum IgE and other test results increased. (2) voluntarily participated in the study; (3) being conscious; (4) Able to communicate in language normally. Donors: (1) Healthy adults aged 18-30 years with no intestinal bacterial or fungal infectious diseases in the past three years, healthy work and rest, no bad living habits such as staying up late, and no use of antibiotics, probiotics or immunomodulators in the past six months; (2) no history of drug and food allergy or long-term medication; (3) without any underlying diseases and infectious diseases; (4) no difficulty falling asleep before or now.
Exclusion criteria
Exclusion criteria: (1) suffering from severe cardiovascular and cerebrovascular diseases, respiratory system diseases, immune system diseases, and severe liver and kidney damage; (2) suffering from severe mental illness, such as depression, generalized anxiety disorder, etc.; (3) patients with intestinal infection or other infectious diseases; (4) patients with allergic reactions to gut microbiota transplantation; (5) patients with intestinal tumors or other intestinal diseases; (6) patients who fail to provide complete medical history or examination data; (7) For various reasons, the study could not be carried out. (8) those with fever, pregnancy, lactation, severe systemic infection, etc.; (9) use of antibiotics in the past 2 weeks; (10) use of probiotics or immunomodulators in the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Questionnaire survey scale;Serum allergen specific IgE;Erythrocyte sedimentation rate;Amplification quantitative culture;Mass spectrum identification;16S rRNA Sequence;Metagenome;C-reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine examination;hepatic and renal function; | — |
Countries
China
Contacts
Public ContactFeng Ninghan
Wuxi No.2 People's Hospital
Outcome results
None listed