Parkinson's disease
Conditions
Interventions
Experimental group:Western medicine treatment combined with GuBen PingChan Formula
Control group:Western medical treatment combined with Placebo
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for MDS idiopathic Parkinson's disease, and accompanied with gait abnormalities; (2) The Hoehn & Yahr stage range is from 1~4; (3) The age range is from 40 to 80 years old, with no gender restrictions; (4) Understands and agrees to participate in this study and has signed an informed consent form; (5) Western medicine treatment: Anti-PD medications and dosages have been relatively stable for at least 3 months prior to this clinical trial, and there are no plans to change the current treatment regimen within the next 3 months.
Exclusion criteria
Exclusion criteria: (1) Suffering from other diseases that cause gait abnormalities; (2) Having parkinsonisms caused by cerebrovascular diseases, encephalitis, poisoning, medications, etc., and patients with Parkinsonism-plus syndromes; (3) Having severe heart, liver, kidney, and other diseases; (4) Having a history of dementia or mental illness; (5) Pregnant and lactating women; (6) Having participated in other clinical studies within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MDS-UPDRS Part ? scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Gait Assessment scores;Time of Timed Up and Go test;Freezing of Gait Questionnaire;MDS-UPDRS Part ?, ?, and ?;MDS Non-Motor Rating Scale;Montreal Cognitive Assessment;Frontal Assessment Battery;Patient Health Questionnaire-9;Generalized Anxiety Disorder-7;Blood pressure and heart rate changes in supine and standing positions;Parkinson’s disease sleep scale version 2;The 39-item Parkinson’s Disease Questionnaire;The Schwab and England Activities of Daily Living;Parkinson's Disease Traditional Chinese Medicine Syndrome Scale; | — |
Countries
China
Contacts
Public ContactYunyun Zhang
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed