A study on the effect and clinical significance of different types of fluid resuscitation on polysaccharide encapsulation in septic shock

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400084714

Enrollment

Unknown

Registered

2024-05-23

Start date

2023-12-20

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic Shock

Interventions

Experimental Group 1:20% human serum albumin 100ml+crystal solution (30ml/kg) will be used for liquid resuscitation

Experimental Group 2:Liquid resuscitation will be performed using "crystal liquid (30ml/kg)+20% human serum albumin 100ml"

Control group:Liquid resuscitation using "crystal liquid (30ml/kg)"

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Sepsis shock patients who meet SEPSIS 3.0 criteria

Exclusion criteria

Exclusion criteria: 1. Age<18 years old, 2. Pregnant women, 3. Short survival time (<24 hours), 4. Refuse to use blood products, 5. Patients with traumatic brain injury, 6. Presence of active bleeding or hemoglobin<70g/L

Design outcomes

Primary

Measure	Time frame
28 day mortality rate;	—

Secondary

Measure	Time frame
Mechanical ventilation days;Dosage of norepinephrine;	—

Countries

China

Contacts

Public ContactXinhui Wu

The Fourth Hospital of Hebei Medical University

sjz_wxh@sina.com+86 136 7316 6177

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026