spine-specific sarcopenia
Conditions
Interventions
Multicenter Spine-Specific Sarcopenia Cohort:This study constitutes a long-term follow-up cohort of elderly individuals undergoing physical examinations, obtaining clinical information, muscle functio
Xinjiekou Community Cohort:This cohort study has completed the baseline data collection, and will continue to complete the follow-up in the second year after enrollment. This project uses both baselin
Sponsors
Laboratory of Bone Tissue Engineering of Beijing Research Institute of Traumatology and Orthopaedics
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Multicenter Spine-Specific Sarcopenia Cohort: 1)Age 60 or above; 2)Gender unrestricted; 3)Informed consent; 4)Autonomous capacity; 5)Willing to cooperate with multiple follow-ups to reduce loss to follow-up. Xinjiekou Community Cohort: 1) Have certain activity ability and autonomous consciousness, and can cooperate to complete the full set of examinations; 2) voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Multicenter Spine-Specific Sarcopenia Cohort: 1)Patients with a history of spinal surgery; 2)Patients known to have congenital spinal deformities; 3)Patients known to have neuromuscular diseases; 4)Patients known to have rheumatic immune diseases (including ankylosing spondylitis); 5)Patients with spinal tumors, infections, or fractures; 6)Lumbar spondylolisthesis > II°, Cobb angle of scoliosis > 30°; 7)Patients with obvious spinal cord compression symptoms; 8)Patients with severe systemic diseases; 9)Patients with cognitive or communication impairments. Xinjiekou Community Cohort: 1) suffering from a serious or life-threatening illness; 2) refused to row CT examination; 3) unable to cooperate with the questionnaire survey; 4) Refusal to sign informed consent.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Basic information;Physical examination of sensation and movement of lower limbs;Spinal muscle function test;Low dose chest CT (LDCT) scan;Daily activity, falls, and nutrition information;Muscle strength and physical function were tested;The living status and fall incidence during the follow-up period were analyzed;Low dose chest CT (LDCT) scan;Muscle strength and physical function indexes; | — |
Primary
| Measure | Time frame |
|---|---|
| Major fracture occurrences; | — |
Countries
China
Contacts
Public ContactYajun Liu
Laboratory of Bone Tissue Engineering of Beijing Research Institute of Traumatology and Orthopaedics
Outcome results
None listed