Painless bronchoscope
Conditions
Interventions
Esketamine Group:Three minutes before the procedure began: Remazolam 0.2mg/kg intravenously
and esketamine 0.3mg/kg and fentanyl 0.5ug/kg 1 minute later
Fentanyl group:Three minutes before the procedure began: Remazolam 0.2mg/kg intravenously, and fentanyl 1.5ug/kg 1 minute later
Sponsors
Deyang People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1 Gender is not limited, age 65-85 years old; 2 Patients with ASA grade I-III who received painless fiberoptic bronchoscopy in our hospital; 3 BMI 18-28 kg/m2; 4 No bronchoscopy contraindications; 5 Able to understand the research process and communicate effectively with researchers; 6 Participate voluntarily and sign informed consent.
Exclusion criteria
Exclusion criteria: 1 Severe hypertension or diabetes; 2 Coronary heart disease and severe pulmonary insufficiency; 3 Head trauma or central nervous system or mental illness; 4 difficult airway or hypoxemia; 5 Drug and/or alcohol abuse; 6 Allergic to research drugs; 7 Glaucoma patients or patients with increased intraocular pressure; 8 Blood system diseases; 9 Obvious abnormal liver and kidney function (that is, the indexes are more than one time higher than normal); 10 Patients who do not accept this test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of fiberoptic operation;recovery time;Incidence of hypertension/hypotension;Time to discharge;Incidence of agitation;QOR-15 rating scale; | — |
Countries
China
Contacts
Public ContactXie An
Deyang People's Hospital
Outcome results
None listed