perimenopausal syndrome
Conditions
Interventions
Experimental group:Royal jelly main protein
Control group (Placebo):Whey protein
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
Female
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: ? Women aged =40 years; ? Regular menstruation, 10 U/L<Serum FSH=40 U/L; ? There are clinical symptoms such as fatigue, insomnia, hot flashes, sweating, mood swings, bone and joint pain and palpitations and so on.
Exclusion criteria
Exclusion criteria: ? Hormone replacement therapy (HRT) was found within 6 months, including phytoestrogens and black cohosh and so on. ? Have a history of allergic diseases; ? Chronic diseases such as liver and kidney dysfunction; ? History of gynecological diseases, such as uterine fibroids. ? The informed consent has not been signed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Kupperman index score;Menopause Rating Scale;Menopause-specific Quality of Life Questionnaire;Pittshurgh sleep quality index;24 hour dietary recalls;international physical activity questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Follicle-stimulating hormone;Luteinizing hormone;Estradiol;Pituitary prolactin;Testosterone;Progesterone;Triglycerides;Total cholesterol;High-density lipoprotein cholesterol;LDL cholesterol;Small, dense LDL cholesterol; | — |
Countries
China
Contacts
Public ContactSheng Ge
Shanghai Sixth People's Hospital
Outcome results
None listed