Acne
Conditions
Interventions
Treatment group:5-Fluorouracil
Control group:Type A botulinum toxin
Sponsors
Plastic Surgery Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age 18 to 65 (included) years old, no gender restriction; (2) Diagnosed with facial acne; (3) Voluntarily join this trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of healing disorders or keloid scars. (2) Patients known to have systemic infections or local infections at the intended treatment site. (3) Patients with a history of immunosuppression/immunodysfunction (including HIV infection or AIDS) or taking immunosuppressive drugs. (4) Patients who have had sunburn within the past month. (5) Patients who have received surgical treatment in the intended treatment area within the past month, including: minimally invasive, plastic surgery, phototherapy, intense pulsed light, laser, radiofrequency treatment. (6) Patients who have taken or are taking anticoagulants or drugs that affect wound healing within the past month. (7) Patients who have taken or are taking or have applied minocycline, isotretinoin, and other acne treatment drugs within the past month. (8) Currently suffering from epilepsy, emotional disorders or cognitive disorders who cannot cooperate with treatment. (9) Pregnant women, breastfeeding women, or those who plan to become pregnant or give birth during the trial period. (10) Those who have participated in other interventional clinical trials within the past month. (11) Other situations where the researcher believes it is not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment Efficacy;Global Aesthetic Improvement Scale;Satisfaction Questionnaire; | — |
Countries
China
Contacts
Public ContactJintian Hu
Plastic Surgery Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed