prostate cancer
Conditions
Interventions
Index test:Through microbial diversity sequencing 16S rRNA and microbial metagenomic sequencing, the significant differences in microbial species, microbial abundance, correlation between relevant mic
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
Male
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: ? According to the diagnostic guidelines of the Chinese Society of Urology, general risk patients aged 50 years or older who underwent PCa early screening were selected from the outpatient and inpatient departments of urology. ? All patients received blood prostate-specific antigen (PSA) and abdominal B-ultrasonography ? The diagnosis of prostate cancer and benign prostatic hyperplasia was confirmed by pathological examination of transrectal prostate biopsy guided by B-ultrasound or transurethral resection of the prostate combined with histopathological examination ? Patients were informed of the relevant trial procedures and signed informed consent
Exclusion criteria
Exclusion criteria: ? Previously received anti-androgenesis, castration, radiotherapy, chemotherapy and other treatments; Patients with other neoplastic diseases ? Contraindications of ultrasound-guided transrectal prostate biopsy: coagulation disorders and urogenital tract infection ? Patients who had previously received puncture biopsy and underwent related prostate surgery ? Received systemic antibiotic therapy (oral or intravenous) within 1 month before enrollment ? Patients who perform urethral operations such as catheterization or prostatic fluid examination within 1-2 weeks for prostate massage ? Patients who are under guardianship, supervision or are unable to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic relevance;Screening sensitivity; | — |
Secondary
| Measure | Time frame |
|---|---|
| accuracy; | — |
Countries
China
Contacts
Public ContactTao Wu
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed