Hyperlipidemia
Conditions
Interventions
Control:Atorvastatin + placebo
Intervention:Rongqingbaohuashuan powder + atorvastatin
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: = 40 years old and = 75 years old, regardless of gender; 2. Carotid artery ultrasound showed unstable carotid atherosclerosis plaque; 3. Patients diagnosed with hyperlipidemia, after three months of lifestyle intervention, Low density lipoprotein cholesterol = 3.4mmol/L; 4. Screening for spatiotemporal abdominal triglycerides = 5.6mmol/L; 5. Hyperlipidemic patients who have not taken lipid-lowering drugs or are currently taking lipid-lowering drugs regularly are willing to discontinue their current lipid-lowering drugs for 2 weeks before taking atorvastatin medication.
Exclusion criteria
Exclusion criteria: 1. Individuals who are allergic to any component of the investigational drug; 2. Patients with past or current clinical diagnosis of heart disease; 3. Patients with previous or current clinical diagnosis of cerebrovascular disease; 4. Patients with past or current clinical diagnosis of kidney disease; 5. Patients with previous or existing clinical diagnosis of diabetes; 6. Patients with previous or current clinical diagnosis of peripheral vascular disease; 7. Previously or currently clinically diagnosed as hypertensive patients; 8. Patients with severe liver disease (liver function alanine aminotransferase (ALT) or aspartate aminotransferase (AST) or total bilirubin above the upper limit of normal values); 9. Creatine kinase (CK) is higher than the upper limit of normal value; 10. Rheumatoid and immune diseases, malignant tumors, etc; 11. Various acute and chronic infectious diseases and acute metabolic disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood fat; | — |
Secondary
| Measure | Time frame |
|---|---|
| Carotid atherosclerotic plaque;HCY;Inflammatory factors; | — |
Countries
China
Contacts
Public ContactCheng Mei
Qilu Hospital of Shandong University
Outcome results
None listed