The effect of postoperative application of hydroxycodone on sleep disorders after esophageal and gastric variceal ligation surgery

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400084620

Enrollment

Unknown

Registered

2024-05-21

Start date

2024-05-23

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep disorders after esophageal and gastric varicose vein ligation surgery

Interventions

oxycodone group:After surgery, the oxycodone group (Group O) was connected to a patient controlled intravenous analgesia pump: oxycodone hydrochloride 0.5mg/kg+sodium chloride injection to 100ml, with

control group:Patients do not need PCIA after surgery, and pain relief medication is administered once for pain relief. Remedial measures: According to VAS (Visual Analog Scale/Score), when the patien

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age range from 18 to 65 years old, regardless of gender; During the surgery, intravenous general anesthesia was used; The American Society of Anesthesiologists (ASA) grades II to III.

Exclusion criteria

Exclusion criteria: Long term use of analgesics or sedatives; Hepatic encephalopathy; Neurological disorders (such as Alzheimer's disease or Parkinson's disease); Allergy to experimental drugs; Refuse to sign informed consent form.

Design outcomes

Primary

Measure	Time frame
Sleep quality;	—

Secondary

Measure	Time frame
Postoperative anxiety incidence rate;	—

Countries

China

Contacts

Public ContactKuilin Wu

Liaocheng People's Hospital

330610523@qq.com+86 185 5286 3331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026