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The significance of serum mtDNA and the mechanism of mitochondrial autophagy on ischemia-reperfusion injury in STEMI patients before and after PCI

The significance of serum mtDNA and the mechanism of mitochondrial autophagy on ischemia-reperfusion injury in STEMI patients before and after PCI

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400084612
Enrollment
Unknown
Registered
2024-05-21
Start date
2023-02-23
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

Sponsors

HeBei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: (i) meeting WHO criteria for acute myocardial infarction; (ii) duration of ischaemic chest pain more than 30min; (iii) ECG:ST-segment elevation in 2 or more leads corresponding to the blood supply area, with chest leads at least 0.2 mV and limb leads at least 0.1mV ; (iv)signing informed consent form.

Exclusion criteria

Exclusion criteria: Lack of informed consent

Design outcomes

Primary

MeasureTime frame
mitochondrail DNA copy number;Interleukin 6;Cytochrome C;C reactive protein;

Countries

China

Contacts

Public ContactWangLili

HeBei General Hospital

drwanglili@126.com+86 131 3114 7839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026