hypoxemia
Conditions
Interventions
nasal cannula group:nasal cannula for oxygen
Sponsors
Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People's Republic of China.
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old. 2. Undergoing painless gastroscopy. 3. Population at risk of hypoxemia: meeting any of the following criteria: (1) Age > 60 years old. (2) Frailty (Frail Scale score >= 3). (3) ASA Grade III-IV. (4) Body Mass Index (BMI) >= 30 kg/m^2. (5) History of respiratory sleep apnea or STOP-Bang score >= 3 score. (6) Concurrent heart diseases (left ventricular dysfunction with ejection fraction <= 45%,combined heart, ischemic heart disease, chronic atrial fibrillation, cardiogenic pulmonary edema, hypertension). (7) Concurrent respiratory system diseases (COPD, emphysema, bronchiectasis, asthma, pleural effusion, pulmonary interstitial fibrosis). (8) Diabetes.
Exclusion criteria
Exclusion criteria: 1. Patients with tracheostomy. 2. Patients with conditions such as pneumothorax, mediastinal emphysema, cerebrospinal fluid leakage, cranial trauma, intracranial or extracranial trauma, or intracranial gas accumulation who are not suitable for BiPAP ventilation. 3. Active bleeding or upper gastrointestinal bleeding that has not been effectively controlled. 4. Abnormal liver or kidney function. 5. Patients with large vocal cord polyps, acute pharyngitis, tonsillitis, or acute asthma exacerbations. 6. Patients who are uncooperative or allergic to propofol or emulsifiers. 7. Participation in other clinical studies in the past 3 months. 8. Baseline pulse oximetry saturation <95%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia;Adverse events related to intervention measures; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hypoxemia;Number of occurrences of hypoxemia;Total dose of propofol;Surgical duration;Number of gastroscopy intubations;Duration of sedation;Duration of recovery ;Postoperative satisfaction scores for patients, anesthesiologists, and endoscopists; | — |
Countries
China
Contacts
Public ContactLi Huixin
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed