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The study on the effectiveness of the optimized DICE algorithm in clinical management of behavioral and psychological symptoms of Alzheimer's dementia

Evaluating the effectiveness of the optimized DICE approach in clinical intervention of behavioral and psychological symptoms of dementia in Alzheimer's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084588
Enrollment
Unknown
Registered
2024-05-21
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

behavioral and psychological symptoms of dementia in Alzheimer's disease

Interventions

Optimized DICE approach intervention group:The optimized DICE method intervention includes four steps: 1 Describe: Using comprehensive assessment tools to thoroughly understand the patients BPSD sever
Usual care group:Clinicians do not enforce the use of the optimized DICE approach, but provide clinical treatment based on conventional practices.

Sponsors

Peking University Sixth Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: ? Age between 60 to 85 years old; ? Unlimited gender; ? Clinically diagnosed as dementia according to ICD-10 criteria, and classified as Alzheimer's disease subtype; ? Score of 2 or above on agitation/aggression, disinhibition, irritability/lability, and aberrant motor any item of the Neuropsychiatric Inventory Questionnaire - Informant Version (NPI-Q); ? Having a regular caregiver; ? Patient or their legal guardian consents to participate in a 12-week follow-up.

Exclusion criteria

Exclusion criteria: ? Clinically diagnosed as types of dementia other than Alzheimer's disease; ? With impaired consciousness; ? Those whose impulsive behaviors are dominated by hallucinations (score of 3 on the hallucination item of NPI-Q); ? Presenting with extremely severe behavioral and psychological symptoms (score of 3 on the agitation/aggression item of NPI-Q) requiring emergency antipsychotic treatment; ? With severe physical condition or unstable malignant tumor condition.

Design outcomes

Primary

MeasureTime frame
The score of Neuropsychiatric Inventory (NPI);

Secondary

MeasureTime frame
The score of Neuropsychiatric Inventory (NPI);The score of Caregiver Burden Inventory (CBI);

Countries

China

Contacts

Public ContactWang Huali

Peking University Sixth Hospital

huali_wang@bjmu.edu.cn+86 10 8280 1983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026