halitosis
Conditions
Interventions
Test group:The experimental group was given health education and treatment with Huopu Xialing decoction-free granules.
control group:The control group was given health education and treatment with triple live bifidobacteria.
Sponsors
The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 55 years old (including 18 and 55 years old); 2. Meet the above diagnostic criteria for halitosis, and the Rosenberg score is =2; 3. VSCs value >150ppb for sulfide detection instrument; 4. The area of tongue coating is =2, and the thickness of tongue coating is =2; 5. There is no habit of cleaning the tongue coating; 6. No history of smoking; 7. The course of the disease is = 15 days; 8. Volunteer and be able to participate in the experiment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from upper respiratory tract infection accompanied by oral infection and bad breath caused by hepatobiliary system, urinary system and other diseases; 2. Those with serious primary diseases such as heart, lung, liver, kidney and hematopoietic diseases; 3. Patients with malignant tumors; 4. Women are pregnant, lactating or preparing for pregnancy; 5. There is a mental disorder, which cannot cooperate with or does not cooperate with the treatment; 6. In the past three months, antibiotics, non-steroidal anti-inflammatory drugs, immunosuppressants, probiotics, and prebiotic preparations were used for oral treatment; 7. Have a history of allergies to the ingredients of experimental drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical effectiveness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Volatile Sulfur Compounds, VSCs;Rosenberg rating;Traditional Chinese Medicine syndrome score;Microbial diversity analysis;Tongue coating area and thickness;Security indicators; | — |
Countries
China
Contacts
Public ContactChen Shanshan
The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University
Outcome results
None listed