Allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Age 6-60 years old, both male and female; ? Weight = 40 kg (weight = 30 in young children); ? Clinical manifestations in accordance with the Chinese Guidelines for the Diagnosis and Treatment of Allergic Rhinitis (2022, Revised); and the presence of at least one positive pollen allergen serum-specific IgE test within 1 year; ? The presence of more than 2 (including 2) symptoms such as sneezing, clear watery runny nose, nasal congestion, nasal itching, etc., and the symptoms per day The symptoms of sneezing, clear watery runny nose, nasal congestion, nasal itching, etc. lasted or accumulated for more than 1 h per day, and the single symptom score of runny nose [total nasal symptom score (TNSS)] was =2; ? Subjects voluntarily participated in this study, and the written informed consent was signed by the subjects themselves or their legal guardians. Translated with DeepL.com (free version)
Exclusion criteria
Exclusion criteria: ? Clinically uncontrolled active infections, such as acute upper respiratory tract infections, etc.; ? Use of glucocorticoids, antihistamines, anti-leukotrienes, and decongestant medications within 1 week; ? Combination of other systemic immune disorders; ? Pregnant or breastfeeding women; ? Those who suffer from psychiatric disorders; and ? Those who have undergone sinus surgery within 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-1;IL-6;TNF-a;IgE; | — |
Countries
China
Contacts
Department of Otolaryngology, Head and Neck Surgery, Yantai Yuhuanding Hospital, Yantai, Shandong, China