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Clinical characteristics and mechanism of brain response to allergic rhinitis

Clinical characteristics and mechanism of brain response to allergic rhinitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400084567
Enrollment
Unknown
Registered
2024-05-20
Start date
2024-05-20
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis

Interventions

Control group:None

Sponsors

Department of Otolaryngology, Head and Neck Surgery, Yantai Yuhuanding Hospital, Yantai, Shandong, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 60 Years

Inclusion criteria

Inclusion criteria: ? Age 6-60 years old, both male and female; ? Weight = 40 kg (weight = 30 in young children); ? Clinical manifestations in accordance with the Chinese Guidelines for the Diagnosis and Treatment of Allergic Rhinitis (2022, Revised); and the presence of at least one positive pollen allergen serum-specific IgE test within 1 year; ? The presence of more than 2 (including 2) symptoms such as sneezing, clear watery runny nose, nasal congestion, nasal itching, etc., and the symptoms per day The symptoms of sneezing, clear watery runny nose, nasal congestion, nasal itching, etc. lasted or accumulated for more than 1 h per day, and the single symptom score of runny nose [total nasal symptom score (TNSS)] was =2; ? Subjects voluntarily participated in this study, and the written informed consent was signed by the subjects themselves or their legal guardians. Translated with DeepL.com (free version)

Exclusion criteria

Exclusion criteria: ? Clinically uncontrolled active infections, such as acute upper respiratory tract infections, etc.; ? Use of glucocorticoids, antihistamines, anti-leukotrienes, and decongestant medications within 1 week; ? Combination of other systemic immune disorders; ? Pregnant or breastfeeding women; ? Those who suffer from psychiatric disorders; and ? Those who have undergone sinus surgery within 6 months.

Design outcomes

Primary

MeasureTime frame
IL-1;IL-6;TNF-a;IgE;

Countries

China

Contacts

Public ContactSongXicheng

Department of Otolaryngology, Head and Neck Surgery, Yantai Yuhuanding Hospital, Yantai, Shandong, China

drxchsong@163.com+86 180 0535 0077

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026