Clinical study of Madopar in the treatment of early stage steroid-induced osteonecrosis of the femoral head

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400084562

Enrollment

Unknown

Registered

2024-05-20

Start date

2024-06-01

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Steroid-induced osteonecrosis of the femoral head

Interventions

therapy group:Madopar + Calcium carbonate + Vitamin D3

control group:Calcium carbonate + Vitamin D3

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients in the experimental group met the diagnostic criteria for steriod induced osteonecrosis of the femoral head of the latest version of the Clinical Guidelines, and were treated with oral Levodopa and Benserazide Hydrochloride Tablets. The patients in the control group were diagnosed with steriod induced osteonecrosis of the femoral head and did not receive Levodopa and Benserazide Hydrochloride Tablets treatment.

Exclusion criteria

Exclusion criteria: Patients with lack of follow-up information and cases with unclear diagnosis.

Design outcomes

Primary

Measure	Time frame
radiographic outcomes;Charnley's modification of the Merle d' Aubigné score;patient satisfaction;Performance Status;	—

Secondary

Measure	Time frame
sex;age;height;weight;BMI;	—

Countries

China

Contacts

Public ContactDechun Geng

the First Affiliated Hospital of Soochow University

szgengdc@suda.edu.cn+86 139 1543 9672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026