discogenic low back pain
Conditions
Interventions
Platelet-rich plasma injection group:Injection of autologous-derived platelet-rich plasma into the responsible intervertebral disc in patients with confirmed discogenic low back pain
Sponsors
The First Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Age greater than 18 years (2) Chronic low back pain without leg pain for more than 3 months. (3) One or more lumbar intervertebral discs with evidence of degenerative changes based on MRI (4) Maintain 50% or more of normal disc height (5) Use of standardized provocative discography and confirmation of at least one symptomatic disc. (6) Agree and sign an informed consent form
Exclusion criteria
Exclusion criteria: (1) Those who do not meet the inclusion criteria; (2) Those with a history of serious illness in poor general health, including hematologic disorders and cancer that cannot tolerate surgery; (3) Abnormal neurological symptoms (e.g. radiculopathy) with lumbar spinal stenosis or spondylolisthesis and inflammatory arthritis. (4) Those who meet the inclusion criteria, but the patient requests conservative treatment. (5) Inability to complete follow-up or provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;Numerical Rating Scale;Oswestry disability index score ;Functional Rating Index;fat fraction;Moisture quantification T2 mapping value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Segments of the degenerative disc;number of intraoperative punctures;degree of disc degeneration;postoperative complications; | — |
Countries
China
Contacts
Public ContactJie Hao
The First Hospital of Chongqing Medical University
Outcome results
None listed