Vasomotor symptoms after endocrine therapy for breast cancer
Conditions
Interventions
Treatment group :Zishui Qinggan Yin granules
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) It meets the VMS diagnostic criteria of western medicine for breast cancer after endocrine therapy. (2) Meets the traditional Chinese medicine syndrome criteria for kidney deficiency and liver depression. (3) Has received endocrine therapy for more than 3 months (such as tamoxifen, toremifen, goserelin, leuprorelin, etc.) and is currently undergoing regular endocrine therapy. (4) The frequency of VMS attacks exceeding 21 times per week. (5) Women over 18 years old who have not menopaused. (6) Expected survival time = 6 months and KPS score = 70 points. (7) Patients voluntarily participate in this study, can be followed up, and sign an informed consent form for treatment before enrollment.
Exclusion criteria
Exclusion criteria: (1) Tumor recurrence or metastasis has occurred. (2) Patients who cannot adhere to endocrine drug treatment during the trial period. (3) Postmenopausal women or those with a history of severe organic lesions in the uterus and ovaries or a history of surgery, or those who have already experienced menopausal VMS before endocrine therapy. (4) The relevant medical records of breast cancer are incomplete. (5) Patients who have used other drugs or treatments to intervene in ovarian function at least 4 weeks prior to the start of the study. (6) Individuals who are allergic to the drugs used in this study or unable to take traditional Chinese medicine treatment normally. (7) Participants in clinical trials of other drugs. (8) Individuals with severe cardiovascular and cerebrovascular diseases, mental illnesses, or severe impairment of liver and kidney function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity score of VMS ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improved Kupperman rating;Traditional Chinese Medicine Syndrome Scoring; | — |
Countries
China
Contacts
Public ContactMa Jing
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion
Outcome results
None listed