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Research on cells in the tumor microenvironment of triple-negative breast cancer

Research on depicting the atlas of cells in the tumor microenvironment of triple-negative breast cancer and its correlation with treatment efficacy

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400084513
Enrollment
Unknown
Registered
2024-05-20
Start date
2023-12-08
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Case series:None

Sponsors

Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Patients were diagnosed with triple-negative breast cancer according to the standards of the NCCN guidelinesfor breast cancer (2023); 2) Patients are planned to receive neo-adjuvant chemotherapy based on pre-operative imaging and labratory examination; 3) Patients were female in gender with ages in the range of 18-60 years, and expected to live for more than 3 months; 4) Patients (or guardians of patients) were free to choose to whether attend this study or not after being educated on the benefits and potential discomorts in attending this study.

Exclusion criteria

Exclusion criteria: 1) Patients attended other clinical trials within 3 months; 2) Patients diagnosed with malignancy in other organs/tissues; 3) Patients with severe cardiopulmonary, renal, or intracranial disorders; 4) Patients evaluated as not able to tolerate chemotherapy according to the assessement of the functional states of organs; 5) Patients considered as not suitable for this study; 6) Patients (or guardians of patients) not willing to attend this study.

Design outcomes

Primary

MeasureTime frame
The absolute number and proportions of different sub-populations of cells;The differentially expressed genes between cell sub-populations;

Countries

China

Contacts

Public ContactYandan Yao

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

yaoyand@mail.sysu.edu.cn+86 138 2629 2688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026