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cfRNA protective fluid improves the diagnostic performance of RNA-related genomic testing in the supernatant of percutaneous biopsy specimens from non-small cell lung cancer

cfRNA protective fluid improves the diagnostic performance of RNA-related genomic testing in the supernatant of percutaneous biopsy specimens from non-small cell lung cancer

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400084508
Enrollment
Unknown
Registered
2024-05-17
Start date
2024-05-20
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Adding or not adding a cfRNA protection fluid groups:None

Sponsors

Beijing Hospital, National Center of Gerontology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Signed informed consent, age > 18 and < 90 years old; (2) Patients with NSCLC who are pathologically confirmed to have NSCLC with any stage according to the 9th edition TNM of the International Association for the Study of Lung Cancer; (3) Provide clinical and pathological data required for research during the treatment process, and agree to use the test data for subsequent research and product development

Exclusion criteria

Exclusion criteria: (1) suffering from other malignant tumors or severe multiple organ dysfunction; (2) It is not appropriate to accept CNB after assessment; (3) The tissue samples obtained by CNB did not meet the requirements for tumor driver gene detection; (4) any other conditions that the study physician considers inappropriate for participation in this clinical trial.

Design outcomes

Primary

MeasureTime frame
cfDNA&cfRNA concentration;

Secondary

MeasureTime frame
Threshold CT values for cfRNAs;The effectiveness of the cfRNA protection solution;Concordance rate of RNA-related gene testing;

Countries

China

Contacts

Public ContactXiao-Guang Li

Beijing Hospital, National Center of Gerontology

xglee88@126.com+86 136 8338 3783

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026