Type II diabetes mellitus with cognitive dysfunction
Conditions
Interventions
Multi-component exercise group:1 Preparatory activities : ( 30 seconds for each action ) Knee lifting and pressing, hip hitting, elbow touching on the opposite side, kicking shuttlecock, sumo deep squ
Sponsors
Shandong Sport University
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: Refer to the diagnostic criteria of T2D in the " Clinical Guidelines for the Prevention and Treatment of Type 2 Diabetes in the Elderly in China ( 2022 Edition ) " promulgated by the Diabetes Society of the Chinese Medical Association in 2022. ? FBG = 7.0 mmol / L ; ? 2 h postprandial blood glucose = 11.1 mmol / L ; ? HbA1c = 6.5 % ; ? diagnosed as type 2 diabetes or using hypoglycemic drugs. Type 2 diabetes can be diagnosed if any of the above conditions are met. The diagnostic criteria of MCI refer to the ' 2018 Chinese Guidelines for the Diagnosis and Treatment of Dementia and Cognitive Impairment ( 5 ) : Diagnosis and Treatment of Mild Cognitive Impairment ', mainly including : 1 patients or informed persons, or experienced clinicians found cognitive impairment ; 2 There was objective evidence of damage in one or more cognitive function areas ; 3 Complex instrumental daily ability can have slight damage, but maintain independent daily life ability ; 4 has not yet reached the diagnosis of dementia. ? Meet the T2D standard ; ? Meet the MCI criteria ; ? Life can take care of itself ; ? Between 60 and 75 years old ; ? In the last six months, there is no regular exercise more than three times a week, more than 30 minutes each time ; ? Subjects informed consent, voluntary participation ; only those who meet all the above conditions can be included in the study.
Exclusion criteria
Exclusion criteria: ?Fasting blood glucose > 16.7mmol / L, recurrent hypoglycemia or severe fluctuations, exercise-induced hypoglycemia or blood glucose less than 4.0mmol / L ; ? Patients with hypertension whose blood pressure could not be controlled ; ? Had a history of severe alcohol and drug abuse ; ? Patients with cognitive impairment caused by depression ; ?Patients with cognitive dysfunction caused by poisoning or drugs and other reasons ; ?Have regular exercise habits ; ? Patients with a history of mental illness, or suffering from severe aphasia and visual impairment, or accompanied by severe organ failure, musculoskeletal system disease, history of coronary heart disease, history of myocardial infarction, musculoskeletal system disease and other contraindications to exercise therapy ; ? Is participating in other clinical trials and will affect the outcome evaluators of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Near infrared brain imaging;Montreal Cognitive Assessment;Mini-Mental State Examination;Cognitive function subdomain test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum biochemical indexes;Functional fitness test; | — |
Countries
China
Contacts
Public ContactSun Zhiyuan
Shandong Sport University
Outcome results
None listed