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Safety and efficacy of personalized delayed anticoagulation in reducing perioperative bleeding in patients with ecchymosis after total joint arthroplasty

Safety and efficacy of personalized delayed anticoagulation in reducing perioperative bleeding in patients with ecchymosis after total joint arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084440
Enrollment
Unknown
Registered
2024-05-16
Start date
2024-05-20
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ecchymosis

Interventions

Ecchymosis individualized delayed anticoagulation group:Delayed use of anticoagulants in patients with ecchymosis
Patients with ecchymosis routine anticoagulation group:Routine anticoagulation treatment

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Age =18 years old; 2) Patients in the Department of Orthopedics of our hospital who need to undergo initial routine hip and knee replacement surgery.

Exclusion criteria

Exclusion criteria: 1) Complicated with severe cardiovascular and cerebrovascular diseases (myocardial infarction, cerebral infarction, etc.); 2) There is a significant bleeding tendency (such as gastrointestinal active bleeding, cerebral hemorrhage, etc.); 3) Combined with systemic or local venous thromboembolism (such as deep vein thrombosis, pulmonary embolism, etc.); 4) Previously defined coagulation dysfunction; 5) Complicated with severe neuromuscular system diseases; 6) Receive a bilateral TKA/THA or a renovated TKA/THA 7) Pregnant or breastfeeding;

Design outcomes

Primary

MeasureTime frame
Blood routine examination;coagulogram;thromboelastogram;Perioperative venous thromboembolism (VTE): deep vein thrombosis (DVT) and pulmonary embolism (PE);

Secondary

MeasureTime frame
Surgical related complications;

Countries

China

Contacts

Public ContactHuang Wei

The First Affiliated Hospital of Chongqing Medical University

huangjiaxingys@163.com+86 23 8901 1202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026