Sarcopenia
Conditions
Interventions
IPC:Ischemic preconditioning intervention on the non-dominant leg, three times a week, with each session consisting of five cycles of pressurization and release at 200mmHg. To be completed at home.
Resistance training:The intervention is carried out using an ankle resistance exercise device. This device allows the user to perform ankle dorsiflexion and plantarflexion movements and offers adjusta
Control:None
Sponsors
Central China Normal University, School of Physical Education and Sport
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age between 60-75 years, in good health, with a BMI less than or equal to 30; 2) No lower limb injuries in the past year; 3) Free from diseases like diabetes, cardiovascular diseases, and musculoskeletal disorders of the lower limbs that could affect the study results; 4) Not taking any medications that could impact the musculoskeletal system and vascular health; 5) Not currently participating in, nor planning to engage in, any regular physical exercise programs at the time of selection; 6) No contraindications for magnetic resonance imaging (MRI); 7) Blood pressure below 160/100.
Exclusion criteria
Exclusion criteria: 1) Diseases of the lower limb musculoskeletal system, cardiovascular diseases, diabetes, or recent lower limb injuries; 2) Currently participating in regular physical exercise or planning to engage in regular physical exercise programs; 3) Various objective reasons that may prevent the completion of the intervention and testing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition and bone mineral density;Muscle morphology;Muscle volume;Muscle quality;Bone architecture;Muscle oxidative capacity;Muslce microvascular function;Ankle muscle force;Static balance;Jump ability;Gait;Six minute walk;VO2max;Physical activity;Quality of life questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Handgrip strength;Timed up and go;30s sit2stand;Y balance; | — |
Countries
China
Contacts
Public ContactChuan Zhang
Central China Normal University
Outcome results
None listed