irritable bowel syndrome
Conditions
Interventions
True stimulation group:TMS stimulates individualized left dorsolateral prefrontal cortex targets
Sham stimulation group:rTMS sham stimulation
Sponsors
Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: Meet the Rome IV diagnostic criteria of IBS; Have stopped taking related drugs for more than 2 weeks; Aged between 18 and 59; Cognitive ability to consent to treatment, understand research instructions and questionnaires.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following criteria will be excluded from the study: have contraindications to MRI and TMS; Mental illness; Women who are pregnant, breastfeeding or preparing for pregnancy during the observation period; Signs of serious illness and/or indications of hospitalization, including hemodynamic instability, infection, acute myocardial infarction and cerebral infarction; In the past 3 months, people have taken any food (such as probiotics, prebiotics, etc.) that affects the test indicators involved in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of irritable bowel syndrome;Degree of depression and anxiety;Imaging indicators of brain function; | — |
Secondary
| Measure | Time frame |
|---|---|
| pain degree;quality of life ; | — |
Countries
China
Contacts
Public ContactJie Li
Affiliated Hospital of Hangzhou Normal University
Outcome results
None listed