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A randomized double-blind prospective study of the effect of pre-infusion of sufentanil on etomidate-induced myasthenia gravis

A randomized double-blind prospective study of the effect of pre-infusion of sufentanil on etomidate-induced myasthenia gravis

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084414
Enrollment
Unknown
Registered
2024-05-16
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

muscle cramp

Interventions

Group A (pilot group):30s slow static push of solution A, 1 min later intravenous push of 0.3 mg/kg etomidate for 30 s. Subsequent induction was given with solution A', A= total amount of 0.4 µg/kg of
Group B (control group):30s slow static push of solution B, 1 min later intravenous push of 0.3 mg/kg etomidate for 30 s. Subsequent induction was given with solution B', B' = total 0.4 µg/kg of sufen

Sponsors

Shenzhen Guangming District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Laparoscopic gallbladder surgery patients, 18-65 years old, ASAI-II class, BMI 16-26 kg/m^2

Exclusion criteria

Exclusion criteria: Patients with known allergies to anesthetic drugs and diseases with neuromuscular dysfunction, such as epilepsy.

Design outcomes

Primary

MeasureTime frame
muscle cramp;intragastric pressure;

Countries

China

Contacts

Public ContactQuanjun Zeng

Shenzhen Guangming District People's Hospital

790378990@qq.com+86 181 8869 0960

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026