None
Conditions
Interventions
Nonvolemic response rehydration group:Within 20min before surgery, 500ml of hydroxyethyl starch 130/0.4 sodium chloride injection and 50ml of normal saline were continuously pumped at 0.05µg/kg/min un
Nonvolemic response norepinephrine group:The loading volume of norepinephrine 4 µg + 0.05 µg/kg/min was intravenously pushed 20 minutes before operation, and the pump was continued until the fetus was
A volume response rehydration group:Within 20min before surgery, 500ml of hydroxyethyl starch 130/0.4 sodium chloride injection and 50ml of normal saline were continuously pumped at 0.05µg/kg/min unti
A volume response to norepinephrine group:The loading volume of norepinephrine 4 µg + 0.05 µg/kg/min was intravenously pushed 20 minutes before operation, and the pump was continued until the fetus wa
Sponsors
Department of Anesthesiology, The first affiliated Wannan Medical College(Yijishan Hospital of Wannan Medical college)
Eligibility
Sex/Gender
Female
Age
18 Years to 48 Years
Inclusion criteria
Inclusion criteria: ASAI-II, regular prenatal visits, age = 18 years, singleton pregnancy, = 37 weeks' gestation
Exclusion criteria
Exclusion criteria: Gestational hypertension, preeclampsia or emergency cesarean section or 50% history of common carotid artery stenosis, cardiovascular and cerebrovascular diseases, hypertension, chronic obstructive pulmonary disease, arrhythmia, diabetes, cerebrovascular disease, alcoholism, or pregnant women with psychiatric disorders, as well as severe vision, hearing or intellectual disabilities, speech disorders, unable to communicate or unwilling to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic indicators;Intraoperative adverse events occurred;Umbilical cord blood gas index;Postoperative adverse events occurred;Neonatal Apgar score (1 min and 5 min);Duration of postoperative ventilation;Time to get out of bed after surgery; | — |
Countries
China
Contacts
Public ContactChen Yongquan
Department of Anesthesiology, The first affiliated Wannan Medical College(Yijishan Hospital of Wannan Medical college)
Outcome results
None listed