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Clinical study on the efficacy and safety of adebrelimab in the treatment of patients with gastrointestinal tumors

Clinical study on the efficacy and safety of adebrelimab in the treatment of patients with gastrointestinal tumors

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084387
Enrollment
Unknown
Registered
2024-05-15
Start date
2024-05-16
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive tract tumors

Interventions

Adebrelizumab group:The administration regimen of Adebrelizumab is intravenous drip (without prophylactic medication), 1200mg, administered once every 3 weeks. A joint plan is provided by clinical doc

Sponsors

Dengzhou People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age = 18 years old, regardless of gender; 2. Patients with esophageal cancer, gastric cancer, colorectal cancer, biliary tract tumors confirmed by histology or cytology, and patients with liver cancer confirmed by imaging; 3. Patients who cannot undergo surgical resection; 4. At least measurable lesions (according to RECIST 1.1 requirements, the spiral CT scan length of the measurable lesion should be = 10mm or the short diameter of the enlarged lymph nodes should be = 15mm); 5. The researchers determined that the patient can accept the administration of adebrelimab; 6. Voluntarily participate in this study, sign an informed consent form, have good compliance, and cooperate with follow-up.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Individuals who are allergic to adelbilimumab and its excipients; 3. The researcher determines other situations that are not suitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Progression free survival;Objective Response Rate;Disease Control Rate;

Secondary

MeasureTime frame
Overall survival;

Countries

China

Contacts

Public ContactKang Tairong

Dengzhou People's Hospital

874231960@qq.com+86 138 3772 4980

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026