general anesthesia
Conditions
Interventions
extubation under deep anesthesia+HFNC (Group:H):Group H:Propofol maintenance, NI was 65-79, TOF =90%, respiration was regular and at a frequency of 10-15 breaths/min, tidal volume =5mL/kg, extubation,
routine extubation (Group:M):Group M: Extubation was performed when fully awake and could be performed as instructed, TOF =90%, NI =95, VT =6mL/kg, f =12 beats/min, stopping oxygenation SpO2 =95%, ext
Sponsors
THE FIRST AFFILIATED HOSPITAL OF WANNAN MEDICAL COLLEGE
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing thoracoscopic lobectomy at selected time 2. Age: 18-65 years old 3. BMI < 30kg/m² 4. ASA grade I ~ II
Exclusion criteria
Exclusion criteria: 1.Patients with difficult airway or obstructed nasopharyngeal ventilation 2.Patients with unfavorable intubation process 3.Patients with a history of neuropsychiatric disease before surgery 4. Patients with myasthenia gravis or suspected myasthenia gravis 5. patients with more than 3 hours of operation 6. patients with a full stomach, patients with recurrent laryngeal nerve or airway injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-extubation hypoxemia (defined as SpO2 <90% for =5S); | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate,HR;mean arterial pressure,MAP;respiratory rate,RR;narcotrend Index;arterial partial pressure of oxygen,PaO2;arterial partial pressure of carbondioxide,PaCO2;arterial oxygen saturation,SaO2;Cough score;SAS sedative agitation score;lung ultrasound score,LUS;Aldrete score;Total time to anesthesia resuscitation at PACU;Sputum aspiration times;Sore throat;hearing;The tongue after falling;Incidence of postoperative nausea and vomiting; | — |
Countries
China
Contacts
Public ContactYa Cao
THE FIRST AFFILIATED HOSPITAL OF WANNAN MEDICAL COLLEGE
Outcome results
None listed