knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Meets the diagnostic criteria of traditional Chinese and Western medicine, and belongs to the syndrome differentiation of cold dampness obstruction type in traditional Chinese medicine; ? Between the ages of 40 and 80, with a course of disease exceeding 2 months, and most of the time in the past month, there is knee joint pain; VAS score = 3 points; withThose who are willing to be randomly enrolled for treatment and sign an informed consent form with good compliance. ? Those who agree to randomized treatment and sign an informed consent form with good compliance.
Exclusion criteria
Exclusion criteria: Patients who are unwilling to participate in this study and sign informed consent forms; Patients with severe narrowing of joint space, bony ankylosis, and poor mobility as shown on imaging films; Patients with severe illnesses such as cardiovascular, cerebrovascular, liver, and kidney, as well as psychiatric disorders; Patients with related diseases, such as gout, rheumatoid arthritis, purulent arthritis, osteoma, etc. Pregnant or lactating women.Individuals with skin damage at the operating site;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-1ß;MMP-3; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC;VAS;Knee joint skin temperature; | — |
Countries
China
Contacts
longyan first hospital affiliated to fujian university of medical