emergence delirium
Conditions
Interventions
low-dose esketamine complex Dexmedetomidine group (DK group):The DK group received 0.25 mg / kg esketamine intravenously 10 min before induction of general anesthesia, and dexmedetomidine at 0.5 ug /
Dexmedetomidine group (Group D) : In group D, intravenous injection of isovolume saline 10min before induction, intravenous dexmedetomidine 0.5 ug / kg at the beginning of the operation was completed
Sponsors
Jiangmen City Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: (1) Families with elective adenoidectomy and adenoid tonsillectomy agreed to participate in the study; (2) age 3-7 years, gender; (3) weight 12-26kg, BMI of 18-24 kg/m²; (4) ASA I-II; (5) history of unintentional and lung disease; (6) no abnormal liver and kidney function.
Exclusion criteria
Exclusion criteria: (1) hypertension, intracranial pressure or elevated intraocular pressure; (2) hyperthyroidism; (3) patients with epilepsy and other mental diseases; (4) patients with heart block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of emergence delirium ; | — |
Secondary
| Measure | Time frame |
|---|---|
| ICC score;Intraoperative opioid use;Hemodynamic stability during surgery [HR, MAP, observation nodes including before anesthesia induction (T0), endotracheal tube placement (T1), skin cutting (T2), and tracheal tube extraction (T3)];Wake time, extubation time in PACU, and observation time in PACU;the Ramsay score after awakening;Postoperative pain score (FLACC, 15min, 30min, 60min after extubation);Additional status of sedative drugs during the recovery period;The incidence of perioperative adverse reactions; | — |
Countries
CHINA
Contacts
Public ContactMengjun Situ,Wei Wei
Jiangmen City Maternal and Child Health Care Hospital Guangzhou Women and Children Medical Center
Outcome results
None listed