atelectasis
Conditions
Interventions
group A:The patients were given PEEP 3-4 cmH 20 as needed after the removal of the bronchial blockade tube and the rehabilitation of both lungs. And 100% inhaled oxygen until the endotracheal tube was
group B:The patients were given PEEP 5-6 cmH 20 as needed after the removal of the bronchial blockade tube and the rehabilitation of both lungs. And 100% inhaled oxygen until the endotracheal tube was
group C:The patients were given PEEP 7-8 cmH 20 as needed after the removal of the bronchial blockade tube and the rehabilitation of both lungs. And 100% inhaled oxygen until the endotracheal tube was
Sponsors
Fujian Children's Hospital
Eligibility
Sex/Gender
All
Age
0.1 Years to 1 Years
Inclusion criteria
Inclusion criteria: (1)Children undergoing elective one-lung ventilation thoracoscopic surgery for pulmonary cystadenoma with tracheal catheter external bronchial blockade;(2)There were no obvious anesthesia and surgical contraindications;(3)ASA classification is in grade I-II;(4)Age was less than 1 year old.
Exclusion criteria
Exclusion criteria: (1)The inner diameter of tracheal intubation is less than 3.0 mm; (2)Preoperative lung CT or ultrasound showed atelectasis; (3)Change to bilateral ventilation during operation;(4)The concentration of oxygen inhaled during operation is greater than 90%;(5)PEEP changes during operation;(6)Respiratory and circulatory system dysfunction;(7)Those who refuse to participate in the research project.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Results of blood gas analysis (oxygen and index PaO 2 / FiO 2, AaDO 2) at T1 (end of surgery);Serum injury inflammatory cytokines content including CRP, IL-6, IL-8, IL-10, IFN- ?, and TNF- a at T1 (end of surgery);Results of blood gas analysis (oxygen and index PaO 2 / FiO 2, AaDO 2) at T2 (one hour after extubation);Serum injury inflammatory cytokines content including CRP, IL-6, IL-8, IL-10, IFN- ?, and TNF- a at T2 (one hour after extubation);T2 time point bedside chest radiograph and lung ultrasound atelectasis score;Prevalence of postoperative hypoxemia (SPO 2 <90%); | — |
Secondary
| Measure | Time frame |
|---|---|
| General preoperative condition (gender, age, body weight);Hemodynamic indicators (mean arterial blood pressure, central venous pressure, heart rate)T1 (end of surgery).;Hemodynamic indicators (mean arterial blood pressure, central venous pressure, heart rate)T2 (one hour after extubation).;Number of days in hospital after surgery; | — |
Countries
China
Contacts
Public ContactLingshan Yu
Fujian Children's Hospital
Outcome results
None listed