Gastrointestinal and gynecological tumors
Conditions
Interventions
Experimental Group:The mechanical power-directed ventilation strategy group (experimental group) was set as inspiratory pause 20%, recruitment maneuver for 30 min/time and adjusted VT, PEEP, RR, FiO2
Control Group:The conventional lung protective ventilation strategy group (control group) was set as VT=6-8 ml/kg (ideal body weight), PEEP=8 cmH2O, RR: 12-20 beats/min, inspiratory: expiratory ratio
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: ?Adult patients undergoing elective general anesthesia for lower abdominal laparoscopic surgery; ?ARISCAT score (Respiratory Risk Assessment for Surgical Patients in Catalonia) =26; ?preoperative VAS pain score =3 and voluntary use of PCIA analgesia in the postoperative period; ?ASA classification I-III; ? expected duration of general anesthesia more than 2 hours.
Exclusion criteria
Exclusion criteria: ? Mechanical power-directed ventilation strategy was unable to maintain oxygen saturation = 95% and PetCO2 = 65 mmHg; ? history of previous lung surgery; ? body mass index higher than 40 kg/m²; ? severe chronic obstructive pulmonary disease (FEV1 < 30% of the predicted value); ? severe cardiac disease; ? emergency surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative and in-PACU hypoxemia;Arterial blood gas analysis before intubation, after intubation, before awakening, and 15 min after extubation;Proportion of unplanned ICU admissions; | — |
Countries
China
Contacts
Public ContactJiru Zhang
Affiliated Hospital of Jiangnan University
Outcome results
None listed