dry eye associated with video-terminal syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 18 years old and 60 years old; 2.Use computer to work for no less than 4 hours per day; 3.A diagnosis of dry eye according to DEWSII and also meet the following two conditions: OSDI score ranges from 18 to 80 and NIBUT less than 8 seconds; 4.The best-corrected visual acuity in either eye is =10/50; 5.The intraocular pressure in either eye is within the range of 10-21 mmHg; 6.Voluntarily participates in this study and signs the informed consent form; 7.The right eye is the study eye;
Exclusion criteria
Exclusion criteria: 1.With ocular diseases, such as meibomian gland dysfunction, allergic conjunctivitis, Demodex blepharitis, keratitis, conjunctivitis, glaucoma, retinal diseases and other diseases that affect ocular surface parameters and fundus blood flow; 2.Corneal or intraocular surgery, radiotherapy, and laser therapy in the past 6 months; 3.With systemic diseases such as Sjögren syndrome, Steven-Johnson syndrome, graft-versus-host disease, various connective tissue and collagen vascular diseases, severe liver dysfunction, thyroid dysfunction, diabetes and gout, vitamin A deficiency, androgen deficiency, depression, mania, etc; 4.Systemic medications, such as menopausal hormone supplementation, antidepressant, antihistamine, anticholinergic, antipsychotic drugs, isotretinoin drugs, diuretics, contraceptive drugs, systemic chemotherapy drugs, etc; 5.Topical medications, such as ocular antiviral drugs, anti-glaucoma drugs, preservative-containing eye drops, eye ointments, etc; 6.Dry eye treatments other than artificial tears should be performed within 3 months, such as hot and cold compresses, meibomian gland massage, intense pulsed light, etc; 7.People who have a disability, communication barrier, or are unable to complete the test; 8.Other populations that are considered unsuitable by the investigators to participate in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the change of non-invasive tear film break up time;the change of OSDI score;Number of occurrences of adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| the change of eye redness;the change in the thickness of the lipid layer of the tear film; | — |
Countries
China
Contacts
The Zhongshan Ophthalmic Center,Sun Yat-sen University